Endocrine Abstracts

Introduction: 48, XXYY is a rare sex chromosome aneuploidy, being estimated to occur in 1:18000–1:40000 male births. Phenotypically it was considered a variant of Klinefelter syndrome (47,XXY), but currently, due to mental deficiency and behavioural characteristics associated, it’s considered to be a separated genetic condition.Case report: We report a case of a 8-year-old boy, first child of a young non-consanguineous couple, born at term. Due...

Introduction: Primary adrenal insufficiency (PAI) is a potentially life – threatening condition. About 75–80% of cases of PAI are caused by autoimmune destruction, while TB accounts for 7–20% of cases; however, adrenal tuberculosis is still the primary cause of PAI in developing countries. Adrenal tuberculosis is difficult to diagnose because symptoms are non-specific. Moreover, if the patient had no prior contact with TB patients, no past history of pulmonary T...

Introduction: Synchronous medullary thyroid cancer and pHPT is common in MEN-2A (Sipple syndrome). In contrast, concomitant nonmedullary thyroid cancer and primary hyperparathyroidism (PHPT) is very rare even if the pathological relationship between parathyroid and thyroid diseases is common.Aim: Was to determine the prevalence of non-medullary thyroid carcinoma in patient who underwent neck exploration for PHPT.Patients and method...

Introduction: The prevalence of acromegaly is estimated to be 6-28/100000 but several studies suggest that acromegaly is underdiagnosed and its prevalence is underestimated.Aim: To measure the prevalence of clinically relevant acromegaly in a well-defined population using data from 01.04.2004 to 01.11.2016.Method: Cross-sectional study performed in 8 counties from the North-East Romania. Data of patients with acromegaly were collec...